PAK1 anticorps
Aperçu rapide pour PAK1 anticorps (ABIN7605844)
Antigène
Voir toutes PAK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Anti-PAK1 Monoclonal Antibody
-
Attributs du produit
- Anti-PAK1 Monoclonal Antibody. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
-
Purification
- Affinity-chromatography
-
Immunogène
- A synthesized peptide derived from human PAK1 The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-2000IHC 1:50-200ICC/IF 1:50-200IP 1:40FC 1:30
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
-
Date de péremption
- 12 months
-
-
- PAK1 (P21-Activated Kinase 1 (PAK1))
-
Autre désignation
- PAK1
-
Sujet
- P21 (RAC1) activated kinase 1
-
Poids moléculaire
- 73 kDa
-
ID gène
- 5058
-
UniProt
- Q13153
-
Pathways
- Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
Antigène
-