Integrin Alpha2b anticorps (CF®740)
Aperçu rapide pour Integrin Alpha2b anticorps (CF®740) (ABIN7655415)
Antigène
Voir toutes Integrin Alpha2b (CD41) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CD41a(ITGA2B/1036), CF740 conjugate
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Attributs du produit
- Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant full-length human Integrin alpha IIb protein
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Isotype
- IgG1, kappa
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Indications d'application
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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Commentaires
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Positive Control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- Integrin Alpha2b (CD41)
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Autre désignation
- CD41a
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Sujet
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Synonyms: BDPLT16, BDPLT2, GPalpha IIb, GT, HPA3, Integrin alpha IIb, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex
Gene Symbol: ITGA2B
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Poids moléculaire
- 90 kDa
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ID gène
- 3674
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UniProt
- P08514
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Pathways
- Integrin Complex
Antigène
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