TNF alpha anticorps (PE,Cy7)

N° du produit ABIN7670269

L’anticorps Rat Monoclonal anti-TNF alpha a été validé pour ICFC. Il convient pour détecter TNF alpha dans des échantillons de Souris.

Aperçu rapide pour TNF alpha anticorps (PE,Cy7) (ABIN7670269)

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TNF alpha est conjugé à/à la PE,Cy7

Application: Intracellular Flow Cytometry (ICFC)

Clone: XT3-11

Détail du produit anti-TNF alpha anticorps (PE,Cy7)

Fonction: PE/Cyanine7 Anti-Mouse TNFα Antibody[XT3.11]

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant

Conseil sur la manipulation: Please protected from prolonged exposure to light and do not freeze.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months.

Date de péremption: 12 months

Détails sur TNF alpha

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Autre désignation: TNF-alpha

Sujet: Tumor necrosis factor-α,Cachectin,Necrosin,Macrophage cytotoxic factor,Differentiation inducing factor,TNFSF-2,TNF-a,TNF-alpha,TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.

UniProt: P06804

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome