MAP3K7 anticorps (pThr187)
Aperçu rapide pour MAP3K7 anticorps (pThr187) (ABIN7674401)
Antigène
Voir toutes MAP3K7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pThr187
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Fonction
- Phospho-TAK1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: Peptide
Immunogen: peptide
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Isotype
- IgG
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Indications d'application
- WB: 1:5000-1:20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Date de péremption
- 12 months
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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Autre désignation
- TAK1
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Sujet
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Synonyms: MAP3K7|TGF beta activated kinase 1|Mitogen-activated protein kinase kinase kinase 7|mitogen activated protein kinase kinase kinase 7|MAP3K 7
Background: MAP3K7(Mitogen-activated protein kinase kinase kinase 7) is also named TAK1 and belongs to the MAP kinase kinase kinase subfamily. It plays an important role in the cascades of cellular responses evoked by changes in the environment. It has been linked to interleukin-1 receptor and tumor necrosis factor receptor signaling (PMID: 16186825). It has 4 isoforms (53-55 kDa, 64-70 kDa and 75-80 kDa)produced by alternative splicing.
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Poids moléculaire
- 80 kDa
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ID gène
- 6885
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UniProt
- O43318
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Pathways
- Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
Antigène
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