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Haptoglobin anticorps (AA 251-350) (Cy5.5)

HP Reactivité: Humain, Rat, Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN734743
  • Antigène Voir toutes Haptoglobin (HP) Anticorps
    Haptoglobin (HP)
    Épitope
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reactivité
    • 96
    • 41
    • 36
    • 12
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 110
    • 13
    • 9
    • 7
    • 5
    • 2
    Lapin
    Clonalité
    • 128
    • 17
    Polyclonal
    Conjugué
    • 73
    • 28
    • 11
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Haptoglobin est conjugé à/à la Cy5.5
    Application
    • 104
    • 60
    • 57
    • 21
    • 20
    • 18
    • 13
    • 13
    • 12
    • 12
    • 12
    • 11
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificité
    This protein may interact with Peptidase S1 Domain in LPA.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Hpt
    Isotype
    IgG
    Top Product
    Discover our top product HP Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Haptoglobin (HP)
    Abstract
    HP Produits
    Synonymes
    anticorps HP, anticorps wu:fb64e01, anticorps BP, anticorps HP2ALPHA2, anticorps HPA1S, anticorps HP-1, anticorps HPR, anticorps Zonulin, anticorps haptoglobin, anticorps haptoglobin-like, anticorps HP, anticorps hp, anticorps Hp, anticorps LOC479668, anticorps LOC101102413
    Sujet

    Synonyms: BP, HPA1S, HP2ALPHA2, Haptoglobin, Zonulin, HP

    Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial, Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

    ID gène
    3240
    UniProt
    P00738
    Pathways
    Transition Metal Ion Homeostasis
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