PLG anticorps (AA 251-350) (Biotin)

N° du produit ABIN735040

Cet anticorps Lapin Polyclonal détecte spécifiquement PLG dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour PLG anticorps (AA 251-350) (Biotin) (ABIN735040)

Antigène: PLG (Plasminogen (PLG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLG est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PLG anticorps (Biotin)

Épitope: AA 251-350

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PLG

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PLG

Antigène: PLG (Plasminogen (PLG))

Autre désignation: Plasminogen

Sujet:

Synonyms: Plasminogen, Angiostatin, DKFZp779M0222, Microplasmin, Plasmin, Plasmin heavy chain A, PLG, PLMN_HUMAN.

Background: Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200 mg/l. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

ID gène: 5340

UniProt: P00747

Pathways: Système du Complément, Lipid Metabolism