SLC6A4 anticorps (AA 401-500)

N° du produit ABIN735983

Détail du produit anti-SLC6A4 anticorps

Antigène: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Épitope: AA 401-500

Reactivité: Humain, Rat, Souris, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Poulet, Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human 5-HTT

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SLC6A4 (ABIN735983)

Yu, Huang, Zhang, Ye, Chi, Zou, Lv, Zheng: "Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis." dans: World journal of gastroenterology, Vol. 22, Issue 12, pp. 3451-9, (2016) (PubMed).

Wang, Gu, Liu, Bai, Wang: "Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats." dans: Molecular medicine reports, Vol. 15, Issue 2, pp. 673-680, (2016) (PubMed).

Wojtal, Cee, Lang, Götze, Frühauf, Geier, Pastor-Anglada, Torres-Torronteras, Martí, Fried, Lutz, Maggiorini, Gassmann, Rogler, Vavricka: "Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 307, Issue 7, pp. G673-88, (2014) (PubMed).

Wang, Liu, Wang, Bai, Zhang, Sun, Wang: "Involvement of serotonin mechanism in methamphetamine-induced chronic pulmonary toxicity in rats." dans: Human & experimental toxicology, (2013) (PubMed).

Dong, Li, Zheng, Mu, Zhang, Liu: "A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats." dans: Journal of ethnopharmacology, Vol. 150, Issue 3, pp. 1053-61, (2013) (PubMed).

Bai, Wang, Liu, Wang, Lian, Zhang, Kang, Wang: "4-Chloro-DL-phenylalanine protects against monocrotaline‑induced pulmonary vascular remodeling and lung inflammation." dans: International journal of molecular medicine, Vol. 33, Issue 2, pp. 373-82, (2013) (PubMed).

Détails sur SLC6A4

Antigène: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Autre désignation: SLC6A4/5-HTT (SLC6A4 Produits)

Synonymes: anticorps 5-HTT, anticorps 5-HTTLPR, anticorps 5HTT, anticorps HTT, anticorps OCD1, anticorps SERT, anticorps SERT1, anticorps hSERT, anticorps AI323329, anticorps Htt, anticorps Sert, anticorps CG4545, anticorps DmSERT, anticorps DmSerT, anticorps Dmel\\CG4545, anticorps dSERT, anticorps dSERT1, anticorps dSerT, anticorps dSert, anticorps dsert, anticorps SLC6A4, anticorps solute carrier family 6 member 4, anticorps solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, anticorps Serotonin transporter, anticorps huntingtin, anticorps solute carrier family 6 (neurotransmitter transporter), member 4b, anticorps solute carrier family 6 (neurotransmitter transporter), member 4a, anticorps SLC6A4, anticorps Slc6a4, anticorps SerT, anticorps LOC100540532, anticorps slc6a4, anticorps slc6a4b, anticorps slc6a4a

Sujet:

Synonyms: HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR, Sodium-dependent serotonin transporter, 5HT transporter, Solute carrier family 6 member 4, SLC6A4

Background: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.

ID gène: 6532

UniProt: P31645