Recombinant TNF alpha anticorps (AA 77-233)

N° du produit ABIN7795751

Cet anticorps Lapin Monoclonal détecte spécifiquement TNF alpha dans WB et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant TNF alpha anticorps (AA 77-233) (ABIN7795751)

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TNF alpha est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR330M

Détail du produit anti-TNF alpha anticorps

Épitope: AA 77-233

Fonction: Rabbit anti-TNF-alpha Recombinant Monoclonal Antibody [BLR330M]

Purification: Purified

Immunogène: residues 77-233

Isotype: IgG

Information d'application

Indications d'application: IP,6 μL/mg lysate,WB,11,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur TNF alpha

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Autre désignation: TNF-alpha

Sujet: TNF-alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. TNF-alpha can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF-alpha has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. [taken from NCBI Entrez Gene (Gene ID: 7124)].

ID gène: 7124

UniProt: P01375

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome