Recombinant HMGB1 anticorps (N-Term)

N° du produit ABIN7826123

L’anticorps anti-HMGB1 Monoclonal Lapin est utilisé pour la détection de HMGB1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant HMGB1 anticorps (N-Term) (ABIN7826123)

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HMGB1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: HMV317

Détail du produit anti-HMGB1 anticorps

Épitope: N-Term

Fonction: HMGB1 antibody (HMV317)

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HMGB1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:200

Commentaires:

Positive Control: Colon: A strong HMGB1 positivity should be seen in all cell types.

Product Description/Background: HMGB1 antibody validated for immunohistochemistry on 76 different Normal Tissues

Negative Control: Testis: Spermatids and more mature spermatocytes should be HMGB1 negative.

Protocole: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

Date de péremption: 24 months

Détails sur HMGB1

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Autre désignation: HMGB1

Sujet: Gene Alias: high mobility group box 1,HMG-1,HMG1,HMG3,SBP-1

UniProt: P09429

Pathways: Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome