Recombinant HSP27 anticorps (pSer78)

N° du produit ABIN7828250

L’anticorps anti-HSP27 Monoclonal Lapin est utilisé pour la détection de HSP27 dans des échantillons de Humain. Il a été validé pour WB, IHC, IF et IP.

Aperçu rapide pour Recombinant HSP27 anticorps (pSer78) (ABIN7828250)

Antigène: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP27 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A811

Détail du produit anti-HSP27 anticorps

Épitope: pSer78

Fonction: Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody

Purification: Protein A purified

Immunogène: phosphorylated human HSP27 (Ser78) peptide

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:100-1:500,IF 1:50,IP 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur HSP27

Antigène: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Autre désignation: HSP27

Sujet: SRP,HSPB,HEL-S,HSP,HSPB1,CMT2F,HEL-S-102,HMN2B,HS.76067,HSP27,HSP28,Hsp25,SRP27,28 kDa heat shock protein,DKFZp586P1322,epididymis secretory protein Li 102,Estrogen regulated 24 kDa protein,Estrogen-regulated 24 kDa protein,Heat shock 25 kDa protein 1,Heat shock 27 kDa protein,Heat shock 27kD protein 1,Heat shock 27 kDa protein,Heat shock 27 kDa protein 1,Heat shock 28 kDa protein 1,Heat Shock Protein 27,Heat shock protein beta 1,Heat shock protein beta-1,heat shock protein family B (small) member 1,Hsp 25,HSP 27,Hsp 28,Hsp B1,Stress responsive protein 27,Stress-responsive protein 27,Hsp27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway. Phosphorylation of HSP27 causes a change in its tertiary structure, which shifts from large homotypic multimers to dimers and monomers. It has been shown that phosphorylation and increased concentration of HSP27 modulates actin polymerization and reorganization. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 23 kDa

Observed MW: 27 kDa The actual band is not consistent with the expectation.

UniProt: P04792

Pathways: Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling