Recombinant Integrin Alpha2b anticorps
Aperçu rapide pour Recombinant Integrin Alpha2b anticorps (ABIN7828315)
Antigène
Voir toutes Integrin Alpha2b (CD41) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant CD41 Monoclonal Antibody
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Purification
- Protein A purified
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Immunogène
- Recombinant human CD41 fragment
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- Integrin Alpha2b (CD41)
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Autre désignation
- CD41
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Sujet
- HPA;PPP1R;ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93;GPalpha Iib;Integrin alpha-Iib;Platelet membrane glycoprotein Iib;ITGAB;&alpha-IIb integrin-n;BDPLT16;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;alpha subunit;antigen CD41;antigen CD41);form 2;Integrin;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;integrin αIIbβ3;ITA2B;platelet fibrinogen receptor;platelet glycoprotein IIb of IIb/IIIa complex;platelet specific antigen BAK,Integrin α-IIb/β-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 113 kDa
Observed MW: 128 kDa The actual band is not consistent with the expectation.
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UniProt
- P08514
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Pathways
- Integrin Complex
Antigène
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