Recombinant c-MYC anticorps (pSer62)

N° du produit ABIN7828408

Cet anticorps Lapin Monoclonal détecte spécifiquement c-MYC dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant c-MYC anticorps (pSer62) (ABIN7828408)

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MYC est non-conjugé

Application: Western Blotting (WB)

Clone: A816

Détail du produit anti-c-MYC anticorps

Épitope: pSer62

Fonction: Recombinant Phospho-c-Myc (Ser62) Monoclonal Antibody

Purification: Protein A purified

Immunogène: phosphorylated human c-Myc (Ser62) peptide

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur c-MYC

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Autre désignation: c-Myc

Sujet: BHLHe,MYC BHLHE,MRTL,MYCC,bHLHe39,c-Myc,MYC,MYC BHLHE39,AU016757,Avian myelocytomatosis viral oncogene homolog,c Myc,Class E basic helix-loop-helix protein 39,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,Myc2,myc-related translation/localization regulatory factor,Myelocytomatosis oncogene,Niard,Nird,Oncogene Myc,OTTHUMP00000158589,Proto-oncogene c-Myc,Protooncogene homologous to myelocytomatosis virus,RNCMYC,Transcription factor p64,Transcriptional regulator Myc-A,V-Myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian),V-myc myelocytomatosis viral oncogene homolog(avian),Myc, also known as c-Myc, together with l-Myc and n-Myc, belongs to the Myc family of transcription factors. Myc has a basic helix-loop-helix leucine zipper domain and through heterodimerization can bind and regulate the transcriptional activity of genes. It is a key player in the regulation of cell growth and cell cycle progression and acts as a proto-oncogene. Myc localizes to the nucleus but can also be present in the cytoplasm of certain cancer types. Myc is ubiquitously expressed in almost all cell types and its expression positively correlates with tissue proliferative capacity. Myc is also expressed during embryogenesis. Myc is upregulated in many cancer types, especially in aggressive, poorly differentiated tumors. Mutations in the MYC gene and breakpoint translocations within the MYC gene cause Burkitt lymphoma. In addition, Myc is subject to various post-translational modifications, including phosphorylation, acetylation, and ubiquitinylation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 49 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P01106

Pathways: Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg