Recombinant PDK4 anticorps

N° du produit ABIN7828510

Cet anticorps Lapin Monoclonal détecte spécifiquement PDK4 dans WB. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour Recombinant PDK4 anticorps (ABIN7828510)

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PDK4 est non-conjugé

Application: Western Blotting (WB)

Clone: A735

Détail du produit anti-PDK4 anticorps

Fonction: Recombinant PDK4 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PDK4

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Autre désignation: PDK4

Sujet: PDK,PDHK,Pyruvate dehydrogenase lipoamide kinase isozyme,PDK4 PDHK,PDK4,FLJ40832,mitochondrial,Pyruvate dehydrogenase lipoamide kinase isozyme 4,PDK4 PDHK4,PDHK4,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4,Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase 4,Pyruvate dehydrogenase kinase isoenzyme 4,Pyruvate dehydrogenase kinase isoform 4,Pyruvate dehydrogenase kinase isozyme 4,Pyruvate dehydrogenase kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis. Enhanced PDK4 expression may be caused by the increase in free fatty acids that occurs during starvation. Free fatty acids can activate peroxisome proliferator-activated receptor α (PPARα), and activation of PPARα can promote PDK4 expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 46 kDa

Observed MW: 44 kDa The actual band is not consistent with the expectation.

UniProt: Q16654

Pathways: Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg