Recombinant ERBB4 anticorps

N° du produit ABIN7828663

Cet anticorps Lapin Monoclonal détecte spécifiquement ERBB4 dans IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant ERBB4 anticorps (ABIN7828663)

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ERBB4 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A584

Détail du produit anti-ERBB4 anticorps

Fonction: Recombinant HER4/ErbB4 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human HER4/ErbB4 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: IHC 1:200-1:1000,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur ERBB4

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Autre désignation: HER4/ErbB4

Sujet: ALS,HER,ERBB,Proto-oncogene-like protein c-ErbB,Receptor tyrosine-protein kinase erbB,Tyrosine kinase-type cell surface receptor HER,p180erbB,HER4/ErbB,ALS19,HER4,p180erbB4,ERBB4,HER4/ErbB4,Proto-oncogene-like protein c-ErbB-4,Receptor tyrosine-protein kinase erbB-4,Tyrosine kinase-type cell surface receptor HER4,4ICD,Avian erythroblastic leukemia viral oncogene homolog 4,Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4,E4ICD,EC 2.7.10.1,ERBB4 intracellular domain,HER 4,human epidermal growth factor receptor 4,Mer4,MGC138404,Oncogene ERBB4,Receptor protein tyrosine kinase erbB 4 precursor,Receptor tyrosine protein kinase erbB 4,s80HER4,Tyrosine kinase type cell surface receptor HER4,v erb a avian erythroblastic leukemia viral oncogene homolog like 4,v erb a erythroblastic leukemia viral oncogene homolog 4,Verba avian erythroblastic leukemia viral oncogene homolog like 4,Verba erythroblastic leukemia viral oncogene homolog 4,v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian),VERBB2,V-ERB-B2 avian erythroblastic leukemia viral oncogene homolog 4,HER4/ErbB4, like other receptor tyrosine kinase family members, has four ectodomains, a single transmembrane domain and a cytoplasmic tail containing the active tyrosine kinase domain. By binding to neuregulins and/or EGF family ligands, ErbB4 forms either a homodimer or heterodimer with other ErbB family members, which results in receptor activation and signaling. ErbB4 is ubiquitously expressed with the highest expression occurring in brain and heart. The expression of ErbB4 in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in research studies suggesting that ErbB4 expression is involved in both normal tissue development and carcinogenesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q15303

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway