Recombinant TRIM29 anticorps (AA 1-200)

N° du produit ABIN7858739

Cet anticorps Lapin Monoclonal détecte spécifiquement TRIM29 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant TRIM29 anticorps (AA 1-200) (ABIN7858739)

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TRIM29 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: TRIM29-9257R

Détail du produit anti-TRIM29 anticorps

Épitope: AA 1-200

Fonction: Recombinant TRIM29 (Lung Squamous Cell Carcinoma Marker) Antibody

Specificité: It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 1-200) of human TRIM29 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TRIM29

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Autre désignation: TRIM29

Sujet:

Ataxia telangiectasia group D complementing gene (ATDC), Tripartite motif-containing protein 29 (TRIM29),

A431 cells. Human tonsil or squamous cell carcinoma.

Poids moléculaire: 66kDa

ID gène: 23650, 504115

UniProt: Q14134

Pathways: Signalisation p53, Apoptose, Réparation de l'ADN, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus