JAK1 anticorps (pTyr1034, pTyr1035)

N° du produit ABIN743333

L’anticorps Lapin Polyclonal anti-JAK1 a été validé pour WB, ELISA, IHC (p) et FACS. Il convient pour détecter JAK1 dans des échantillons de Humain et Souris. Il y a 3+ publications disponibles.

Aperçu rapide pour JAK1 anticorps (pTyr1034, pTyr1035) (ABIN743333)

Antigène: JAK1 (Janus Kinase 1 (JAK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-JAK1 anticorps

Épitope: pTyr1034, pTyr1035

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Jak1 around the phosphorylation site of Tyr1034 + Tyr1035

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-JAK1 (ABIN743333)

Huang, Zhou, Li, Ming, Li, Wu, Chen, Zhao: "In vivo and in vitro effects of microRNA-221 on hepatocellular carcinoma development and progression through the JAK-STAT3 signaling pathway by targeting SOCS3." dans: Journal of cellular physiology, Vol. 234, Issue 4, pp. 3500-3514, (2019) (PubMed).

Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." dans: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, (2016) (PubMed).

Détails sur JAK1

Antigène: JAK1 (Janus Kinase 1 (JAK1))

Autre désignation: Jak1 +

Sujet:

Synonyms: Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1, JAK1, JAK1A, JAK1B

Background: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

ID gène: 3716

UniProt: P23458

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response