Recombinant TRIM29 anticorps (AA 1-200)

N° du produit ABIN7868781

L’anticorps anti-TRIM29 Monoclonal Lapin est utilisé pour la détection de TRIM29 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant TRIM29 anticorps (AA 1-200) (ABIN7868781)

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TRIM29 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TRIM29-9257R

Détail du produit anti-TRIM29 anticorps

Épitope: AA 1-200

Fonction: Recombinant Tripartite motif-containing protein 29 Antibody / TRIM29

Purification: Protein A/G affinity

Immunogène: A recombinant fragment (within amino acids 1-200) of human recombinant Tripartite motif-containing protein 29 protein was used as the immunogen for the TRIM29 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Tripartite motif-containing protein 29 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Tripartite motif-containing protein 29 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TRIM29

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Autre désignation: Tripartite motif-containing protein 29

Sujet: Tripartite motif-containing protein 29 (TRIM29) interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

UniProt: Q14134

Pathways: Signalisation p53, Apoptose, Réparation de l'ADN, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus