PDK1 anticorps (AA 114-436)

N° du produit ABIN7870193

Cet anticorps Lapin Polyclonal détecte spécifiquement PDK1 dans WB, FACS et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PDK1 anticorps (AA 114-436) (ABIN7870193)

Antigène: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Détail du produit anti-PDK1 anticorps

Épitope: AA 114-436

Fonction: Pyruvate dehydrogenase kinase 1 Antibody / PDK1

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids Y114-A436) was used as the immunogen for the Pyruvate dehydrogenase kinase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Pyruvate dehydrogenase kinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Pyruvate dehydrogenase kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PDK1

Antigène: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Autre désignation: Pyruvate dehydrogenase kinase 1

Sujet: Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

UniProt: Q15118

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Regulation of Carbohydrate Metabolic Process, Hepatitis C, L'effet Warburg