HMGB1 anticorps (AA 123-153)

N° du produit ABIN7870351

Cet anticorps anti-HMGB1 Polyclonal Lapin (ABIN7870351) détecte spécifiquement HMGB1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour HMGB1 anticorps (AA 123-153) (ABIN7870351)

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HMGB1 anticorps

Épitope: AA 123-153

Fonction: Zebrafish Hmgb1 Antibody / Hmgb1a / Hmgb1b

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Hmgb1a/b recombinant protein (amino acids D123-K153) was used as the immunogen for the Zebrafish Hmgb1 antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Hmgb1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Hmgb1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HMGB1

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Autre désignation: Hmgb1

Sujet: High mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

UniProt: Q6NX86

Pathways: Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome