GZMB anticorps (AA 175-203)
Aperçu rapide pour GZMB anticorps (AA 175-203) (ABIN7871301)
Antigène
Voir toutes GZMB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 175-203
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Fonction
- GZMB Antibody / Granzyme B
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Purification
- Purified
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Immunogène
- A portion of amino acids 175-203 from the human protein was used as the immunogen for the GZMB antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the GZMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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Autre désignation
- GZMB
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Sujet
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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