PAK1 anticorps (AA 2-248)

N° du produit ABIN7871790

L’anticorps anti-PAK1 Polyclonal Lapin est utilisé pour la détection de PAK1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour PAK1 anticorps (AA 2-248) (ABIN7871790)

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PAK1 anticorps

Épitope: AA 2-248

Fonction: p21-activated kinase 1 Antibody / PAK1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids S2-M248) was used as the immunogen for the p21-activated kinase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the p21-activated kinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the p21-activated kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PAK1

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Autre désignation: p21-activated kinase 1

Sujet: Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternative transcripts of this gene have been found, but their full-length natures have not yet been determined. The PAK1 gene is mapped to 11q13-q14 by inclusion within a mapped clone.

UniProt: Q13153

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis