IL4 Receptor anticorps (AA 26-719)

N° du produit ABIN7873015

Cet anticorps anti-IL4 Receptor Polyclonal Lapin (ABIN7873015) détecte spécifiquement IL4 Receptor dans ELISA, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour IL4 Receptor anticorps (AA 26-719) (ABIN7873015)

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL4 Receptor est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IL4 Receptor anticorps

Épitope: AA 26-719

Fonction: Il4 receptor Antibody

Purification: Affinity purified

Immunogène: A rat recombinant partial protein (amino acids I26-E719) was used as the immunogen for the Il4 receptor antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Il4 receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Il4 receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IL4 Receptor

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Autre désignation: Il4 receptor

Sujet: IL4R (INTERLEUKIN 4 RECEPTOR) is a human gene that encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. The IL4R gene is localized to 16p12.1-p11.2 by in situ hybridization and Southern blot analysis of DNA from a panel of mouse-human somatic cell lines. IL4 plays a major role in immunoglobulin E(IgE) production. Its signal is conferred to effector cells through binding to the alpha chain of the IL4 receptor. IL4 interacts with IL4R with high affinity, leading to dimerization with either the common gamma chain,a component of receptors for a number of cytokines, to create a type I receptor, or with IL13RA1 to form a type II receptor.The IL4R gene contains 12 exons and IL4R is a complex of at least 2 components, one of which is a novel affinity converting subunit that is critical for cellular signal transduction. See also IL13RA1 and IL13RA2.

UniProt: Q63257

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process