Recombinant GZMB anticorps (AA 73-187)

N° du produit ABIN7876655

Cet anticorps Souris Monoclonal détecte spécifiquement GZMB dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant GZMB anticorps (AA 73-187) (ABIN7876655)

Antigène: GZMB (Granzyme B (GZMB))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RGZMB-6740

Détail du produit anti-GZMB anticorps

Épitope: AA 73-187

Fonction: Recombinant GZMB Antibody / Granzyme B

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 73-187 was used as the immunogen for the recombinant GZMB antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant GZMB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: GZMB

Sujet: Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease.

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis