GZMB anticorps (AA 73-187)

N° du produit ABIN7876658

Cet anticorps Souris Monoclonal détecte spécifiquement GZMB dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (AA 73-187) (ABIN7876658)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: GZMB-3014

Détail du produit anti-GZMB anticorps

Épitope: AA 73-187

Fonction: Granzyme B Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 73-187) was used as the immunogen for the Granzyme B antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Granzyme B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet: Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease.

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis