GZMB anticorps (AA 73-187)

N° du produit ABIN7876665

L’anticorps anti-GZMB Monoclonal Souris est utilisé pour la détection de GZMB dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour GZMB anticorps (AA 73-187) (ABIN7876665)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: GZB-1

Détail du produit anti-GZMB anticorps

Épitope: AA 73-187

Fonction: Granzyme B Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Granzyme B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis