GZMB anticorps (AA 73-187)

N° du produit ABIN7876666

Cet anticorps anti-GZMB Monoclonal Souris (Clone GZB-1) (ABIN7876666) détecte spécifiquement GZMB dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (AA 73-187) (ABIN7876666)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GZB-1

Détail du produit anti-GZMB anticorps

Épitope: AA 73-187

Fonction: Granzyme B Antibody

Purification: Protein G affinity chromatography

Immunogène: Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Granzyme B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis