GZMB anticorps

N° du produit ABIN7880924

Cet anticorps Lapin Monoclonal détecte spécifiquement GZMB dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (ABIN7880924)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AAHC-7

Détail du produit anti-GZMB anticorps

Fonction: Granzyme B Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Granzyme B / GZMB was used as the immunogen for the Granzyme B antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Granzyme B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Granzyme B antibody at -20oC.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis