HMGB1 anticorps

N° du produit ABIN7881045

L’anticorps anti-HMGB1 Monoclonal Lapin est utilisé pour la détection de HMGB1 dans des échantillons de Humain et Rat. Il a été validé pour WB et IHC (p).

Aperçu rapide pour HMGB1 anticorps (ABIN7881045)

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HMGB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AAC-8

Détail du produit anti-HMGB1 anticorps

Fonction: HMGB1 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human HMGB1 was used as the immunogen for the HMGB1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HMGB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the HMGB1 antibody at -20oC.

Détails sur HMGB1

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Autre désignation: HMGB1

Sujet: High mobility group protein B1 is a multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. [UniProt]

UniProt: P09429

Pathways: Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome