Prothrombin anticorps (AA 97-124) (APC)

N° du produit ABIN7980683

Cet anticorps anti-Prothrombin Monoclonal Souris conjugué à APC (Clone 4G13G9) (ABIN7980683) détecte spécifiquement Prothrombin dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Prothrombin anticorps (AA 97-124) (APC) (ABIN7980683)

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prothrombin est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: 4G13G9

Détail du produit anti-Prothrombin anticorps (APC)

Épitope: AA 97-124

Fonction: Anti-Prothrombin Antibody (monoclonal, 4G13G9) APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Prothrombin recombinant protein (Position: Y97-R124).

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: F2

Sujet:

Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

Gene Full Name: coagulation factor II, thrombin

ID gène: 2147

UniProt: P00734

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling