EGF anticorps (AA 971-1023) (Fluoro550)

N° du produit ABIN7988053

L’anticorps anti-EGF Polyclonal Lapin est utilisé pour la détection de EGF dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour EGF anticorps (AA 971-1023) (Fluoro550) (ABIN7988053)

Antigène: EGF (Epidermal Growth Factor (EGF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGF est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-EGF anticorps (Fluoro550)

Épitope: AA 971-1023

Fonction: Anti-EGF Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human EGF recombinant protein (Position: N971-R1023). Human EGF shares 69.8% amino acid (aa) sequence identity with both mouse,rat EGF.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human EGF recombinant protein (Position: N971-R1023). Human EGF shares 69.8% amino acid (aa) sequence identity with both mouse and rat EGF.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur EGF

Antigène: EGF (Epidermal Growth Factor (EGF))

Autre désignation: EGF

Sujet:

Background: EGF is known as epidermal growth factor. This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. Additionally, it acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Gene Full Name: epidermal growth factor

ID gène: 1950

UniProt: P01133

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation