HBEGF anticorps (AA 63-148) (Fluoro594)

N° du produit ABIN7997049

Cet anticorps Lapin Polyclonal détecte spécifiquement HBEGF dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour HBEGF anticorps (AA 63-148) (Fluoro594) (ABIN7997049)

Antigène: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HBEGF est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-HBEGF anticorps (Fluoro594)

Épitope: AA 63-148

Fonction: Anti-Hbegf Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Hbegf recombinant protein (Position: D63-L148).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HBEGF

Antigène: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Autre désignation: Hbegf

Sujet:

Background: Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. Enables epidermal growth factor receptor binding activity, growth factor activity, and heparin binding activity. Involved in positive regulation of keratinocyte migration, positive regulation of smooth muscle cell proliferation, and wound healing, spreading of epidermal cells. Acts upstream of or within several processes, including epidermal growth factor receptor signaling pathway, positive regulation of peptidyl-tyrosine phosphorylation, and regulation of heart contraction. Located in extracellular space. Is integral component of plasma membrane. Is expressed in several structures, including branchial arch, heart, oral region gland, telencephalon, and tooth. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor).

Gene Full Name: heparin-binding EGF-like growth factor

ID gène: 15200

UniProt: Q06186

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway