PAK1 anticorps (AA 2-248) (HRP)

N° du produit ABIN8018959

Cet anticorps anti-PAK1 Polyclonal Lapin conjugué à HRP (ABIN8018959) détecte spécifiquement PAK1 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PAK1 anticorps (AA 2-248) (HRP) (ABIN8018959)

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-PAK1 anticorps (HRP)

Épitope: AA 2-248

Fonction: Anti-PAK1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PAK1 recombinant protein (Position: S2-M248).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PAK1

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Autre désignation: PAK1

Sujet:

Background: Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternative transcripts of this gene have been found, but their full-length natures have not yet been determined. The PAK1 gene is mapped to 11q13-q14 by inclusion within a mapped clone.

Gene Full Name: p21 (RAC1) activated kinase 1

ID gène: 5058

UniProt: Q13153

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis