TRAF3 anticorps (Middle Region) (Cy3)

N° du produit ABIN8047095

L’anticorps anti-TRAF3 Polyclonal Lapin est utilisé pour la détection de TRAF3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour TRAF3 anticorps (Middle Region) (Cy3) (ABIN8047095)

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-TRAF3 anticorps (Cy3)

Épitope: Middle Region

Fonction: Anti-TRAF3 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat,mouse sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TRAF3, identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TRAF3

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Autre désignation: TRAF3

Sujet:

Background: TRAF3 (TNF Receptor-Associated Factor 3), also called LAP1, CAP1, CRAF1 or CD40BP, is a protein that in humans is encoded by the TRAF3 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. Gross (2012) mapped the TRAF3 gene to chromosome 14q32.32 based on an alignment of the TRAF3 sequence with the genomic sequence (GRCh37). Dadgostar et al. (2003) determined that the coiled-coil domain of mouse T3jam interacted with the isoleucine zipper domain of Traf3. Oganesyan et al. (2006) demonstrated that cells lacking TRAF3 are defective in type I interferon responses activated by several different Toll-like receptors.

Gene Full Name: TNF receptor associated factor 3

Sequence Similarities: Belongs to the TNF receptor-associated factor family. A subfamily.

ID gène: 7187

UniProt: Q13114

Pathways: Signalisation NF-kappaB, Apoptose, Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades