BAK1 anticorps

N° du produit ABIN8119961

Cet anticorps Lapin Monoclonal détecte spécifiquement BAK1 dans WB, IHC, ELISA, IF et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BAK1 anticorps (ABIN8119961)

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BAK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2028

Détail du produit anti-BAK1 anticorps

Fonction: Bak Rabbit mAb

Specificité: This antibody detects endogenous levels of Bak protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur BAK1

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Autre désignation: Bak

Sujet:

Synonyms: BAK1, BAK, BCL2L7, CDN1, Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],

Gene Name: BAK1

Protein Name: Bak

ID gène: 578

UniProt: Q16611

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response