MCL-1 anticorps (pSer159, pThr163)

N° du produit ABIN8122176

L’anticorps anti-MCL-1 Polyclonal Lapin est utilisé pour la détection de MCL-1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour MCL-1 anticorps (pSer159, pThr163) (ABIN8122176)

Antigène: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCL-1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MCL-1 anticorps

Épitope: pSer159, pThr163

Fonction: Mcl-1 (Phospho Ser159/Thr163) Antibody

Specificité: This antibody detects endogenous levels of Human Mcl-1 (phospho-Ser159 or Thr163)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized phosho peptide around human Mcl-1 (Ser159 and Thr163)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MCL-1

Antigène: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Autre désignation: Mcl-1

Sujet:

Synonyms: Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)

Background: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010],

Gene Name: MCL1 BCL2L3

Protein Name: Mcl-1 (Ser159/Thr163)

ID gène: 4170

UniProt: Q07820

Pathways: Signalisation MAPK