Retinoblastoma Binding Protein 8 anticorps (AA 621-720)

N° du produit ABIN762956

L’anticorps Lapin Polyclonal anti-Retinoblastoma Binding Protein 8 a été validé pour ELISA, WB, IHC (p), IHC (fro), IF (cc) et IF (p). Il convient pour détecter Retinoblastoma Binding Protein 8 dans des échantillons de Humain.

Aperçu rapide pour Retinoblastoma Binding Protein 8 anticorps (AA 621-720) (ABIN762956)

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Épitope: AA 621-720

Homologie: Human,Mouse,Rat,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CtIP/RBBP8

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: Ctip

Sujet:

Synonyms: COM1_HUMAN antibody CtBP interacting protein antibody CtBP-interacting protein antibody CtIP antibody DNA endonuclease RBBP8, RBBBP8, RBBP-8, RBBP8, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, RIM, SAE2, Sporulation in the absence of SPO11 protein 2 homolog.

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

ID gène: 5932

Pathways: Cycle Cellulaire, Réparation de l'ADN