SAA anticorps

N° du produit ABIN782007

Détail du produit anti-SAA anticorps

Antigène: SAA (Serum Amyloid A (SAA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SAA est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Detection), ELISA (Capture)

Specificité: This antibody recognizes native and recombinant Human Serum Amyloid A (SAA).

Purification: Affinity Chromatography on Protein A

Immunogène: Human recombinant SAA, conjugated with carrier protein

Clone: B332A

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 5.8 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SAA

Antigène: SAA (Serum Amyloid A (SAA))

Autre désignation: Serum Amyloid A Protein (SAA) (SAA Produits)

Synonymes: anticorps PIG4, anticorps SAA, anticorps SAA2, anticorps TP53I4, anticorps zgc:103580, anticorps saa, anticorps SAA1, anticorps Saa-1, anticorps Saa2, anticorps serum amyloid A1, anticorps serum amyloid A, anticorps serum amyloid A protein, anticorps serum amyloid A-3, anticorps HPS5, biogenesis of lysosomal organelles complex 2 subunit 2, anticorps serum amyloid A2, anticorps serum amyloid A 1, anticorps SAA1, anticorps saa, anticorps LOC476879, anticorps SAA, anticorps SAA3, anticorps HPS5, anticorps SAA2, anticorps Saa1, anticorps LOC100270725

Sujet: The Serum Amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

ID gène: 6288

NCBI Accession: NP_000322

UniProt: P02735