BCAS1 anticorps (C-Term)

N° du produit ABIN783588

Détail du produit anti-BCAS1 anticorps

Antigène: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the carboxy terminus of human BCAS1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur BCAS1

Antigène: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Autre désignation: BCAS1 / NABC1 (BCAS1 Produits)

Synonymes: anticorps AIBC1, anticorps NABC1, anticorps 2210416M21Rik, anticorps 9030223A09Rik, anticorps AI841227, anticorps Band83, anticorps Pmes-2, anticorps BCAS1, anticorps MGC152145, anticorps breast carcinoma amplified sequence 1, anticorps BCAS1, anticorps Bcas1

Sujet: BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein, BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.Synonyms: AIBC1, Breast carcinoma-amplified sequence 1

ID gène: 8537

NCBI Accession: NP_003648

UniProt: O75363