ZEB2 anticorps (C-Term)
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- Antigène Voir toutes ZEB2 Anticorps
- ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZEB2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 18 amino acid peptide near the carboxy terminus of human ZEB2
- Top Product
- Discover our top product ZEB2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- Antigène
- ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
- Autre désignation
- ZFHX1B (ZEB2 Produits)
- Synonymes
- anticorps ZFHX1B, anticorps Zfhx1b, anticorps HSPC082, anticorps SIP-1, anticorps SIP1, anticorps SMADIP1, anticorps 9130203F04Rik, anticorps D130016B08Rik, anticorps Zfx1b, anticorps Zfxh1b, anticorps mKIAA0569, anticorps XSip1, anticorps sip1, anticorps zfhx1b, anticorps si:dkey-52o2.2, anticorps sip1a, anticorps wu:fc92g08, anticorps sip1b, anticorps zinc finger E-box binding homeobox 2, anticorps zinc finger E-box binding homeobox 2 S homeolog, anticorps zinc finger homeobox protein, anticorps zinc finger E-box binding homeobox 2a, anticorps zinc finger E-box binding homeobox 2b, anticorps ZEB2, anticorps Zeb2, anticorps zeb2.S, anticorps zeb2, anticorps zeb2a, anticorps zeb2b
- Sujet
- ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues (3). Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.Synonyms: KIAA0569, SIP1, SMADIP1, Smad-interacting protein 1, ZEB2, ZFX1B, Zinc finger E-box-binding homeobox 2, Zinc finger homeobox protein 1b
- ID gène
- 9839
- NCBI Accession
- NP_001165124
- UniProt
- O60315
- Pathways
- Tube Formation
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