ZC3HAV1 anticorps (C-Term)

N° du produit ABIN783641

Détail du produit anti-ZC3HAV1 anticorps

Antigène: ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZC3HAV1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the carboxy terminus of human ZC3HAV1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ZC3HAV1

Antigène: ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))

Autre désignation: ZC3HAV1 (ZC3HAV1 Produits)

Synonymes: anticorps 1200014N16Rik, anticorps 2900058M19Rik, anticorps 9130009D18Rik, anticorps 9830115L13Rik, anticorps ARTD13, anticorps D6Bwg1452e, anticorps ZAP, anticorps Zap, anticorps FLB6421, anticorps PARP13, anticorps ZC3H2, anticorps ZC3HDC2, anticorps zinc finger CCCH type, antiviral 1, anticorps zinc finger CCCH-type containing, antiviral 1, anticorps Zc3hav1, anticorps ZC3HAV1

Sujet: The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.Synonyms: PRO1677, ZC3HDC2, Zinc finger CCCH domain-containing protein 2, Zinc finger CCCH-type antiviral protein 1, Zinc finger antiviral protein

ID gène: 56829

NCBI Accession: NP_064504

UniProt: Q7Z2W4