NMNAT3 anticorps (Internal Region)

N° du produit ABIN784277

Détail du produit anti-NMNAT3 anticorps

Antigène: NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))

Épitope: Internal Region

Reactivité: Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NMNAT3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-KALGQGQSVK YLLPE

Specificité: This antibody is expected to recognize both reported isoforms (NP_835471.1, NP_001186976.1).

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_653116.1. Genename: Nmnat3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NMNAT3

Antigène: NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))

Autre désignation: NMNAT3 (NMNAT3 Produits)

Synonymes: anticorps PNAT-3, anticorps PNAT3, anticorps 4933408N02Rik, anticorps nicotinamide nucleotide adenylyltransferase 3, anticorps si:ch73-170l17.1, anticorps Nmnat3, anticorps NMNAT3, anticorps si:ch73-170l17.1

Sujet: NMNAT3 belongs to the eukaryotic NMN adenylyltransferase family. Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury. Expressed in lung and spleen with lower levels in placenta and kidney.Synonyms: NMN adenylyltransferase 3, Nicotinamide mononucleotide adenylyltransferase 3

ID gène: 74080

NCBI Accession: NP_653116