CD14 anticorps
Aperçu rapide pour CD14 anticorps (ABIN866061)
Antigène
Voir toutes CD14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD14.
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Positive control: K562 cell lysate. Cellular Localization: Cell membrane
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Purification
- Immunogen affinity purified
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Isotype
- IgG
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Indications d'application
- WB: 1:1,000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 1xTBS (pH7.4), 0.5% BSA, 40% Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- CD14
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Autre désignation
- CD14
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Sujet
- CD14 is a glycophosphatidylinositol-anchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and up-regulates cell surface molecules, including adhesion molecules.
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Poids moléculaire
- 39kDa
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UniProt
- P10810
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
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