EGFR anticorps (C-Term)

N° du produit ABIN870533

L’anticorps Lapin Monoclonal anti-EGFR a été validé pour IHC (p). Il convient pour détecter EGFR dans des échantillons de Humain.

Aperçu rapide pour EGFR anticorps (C-Term) (ABIN870533)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EGFR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: A20-E

Détail du produit anti-EGFR anticorps

Épitope: AA 1120-1135, C-Term

Fonction: Anti-EGFR

Specificité: EGFR

Immunogène: Peptide derived from C-terminal region of human epidermal growth factor receptor (EGFR). Antibody recognizes the epitope between Ser1120 - Asn1135.

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: +2 °C to +8 °C

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR

Sujet: Epidermal Growth Factor Receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, colon and in squamous cell carcinoma.

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins