TFE3 anticorps (AA 303-307)

N° du produit ABIN871655

Détail du produit anti-TFE3 anticorps

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Épitope: AA 303-307

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFE3 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous levels of total TFE3 protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 303-307 (L-D-V-Y-S) derived from Human TFE3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur TFE3

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Autre désignation: TFE3 (TFE3 Produits)

Synonymes: anticorps RCCP2, anticorps RCCX1, anticorps TFEA, anticorps bHLHe33, anticorps F830016E06Rik, anticorps Tcfe3, anticorps Tfe-3, anticorps RGD1559642, anticorps cb873, anticorps zgc:109815, anticorps transcription factor binding to IGHM enhancer 3, anticorps transcription factor E3, anticorps transcription factor binding to IGHM enhancer 3 S homeolog, anticorps transcription factor binding to IGHM enhancer 3a, anticorps TFE3, anticorps Tfe3, anticorps tfe3.S, anticorps tfe3a

Sujet: Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Poids moléculaire: 70 kDa

ID gène: 7030

NCBI Accession: NP_006512

UniProt: P19532