ITGA4 anticorps (AA 1024-1028)

N° du produit ABIN871718

Détail du produit anti-ITGA4 anticorps

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Épitope: AA 1024-1028

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA4 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of total LPAM-1 (Integrin a4, CD49d) protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 1024-1028 (Y-I-N-S-K) derived from Human LPAM-1 (Integrin a4, CD49d) . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: LPAM-1 (Integrin Alpha4, CD49d) (ITGA4 Produits)

Synonymes: anticorps CD49D, anticorps IA4, anticorps LOC100219853, anticorps integrin subunit alpha 4, anticorps integrin alpha 4, anticorps integrin subunit alpha 4 S homeolog, anticorps ITGA4, anticorps Itga4, anticorps itga4.S

Sujet: Integrins a-4/beta-1 (VLA-4) and a-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin a-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin a-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Poids moléculaire: 180 kDa

ID gène: 3676

NCBI Accession: NP_000876

UniProt: P13612

Pathways: Integrin Complex