STAM anticorps (AA 101-200)
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- Antigène Voir toutes STAM Anticorps
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
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Épitope
- AA 101-200
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STAM est non-conjugé
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human STAM
- Isotype
- IgG
- Top Product
- Discover our top product STAM Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
- Autre désignation
- STAM (STAM Produits)
- Synonymes
- anticorps STAM-1, anticorps STAM1, anticorps wu:fv75b10, anticorps zgc:55725, anticorps RGD1564499, anticorps signal transducing adaptor molecule, anticorps signal transducing adapter molecule 1, anticorps Signal transducing adapter molecule 1, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, anticorps STAM, anticorps CpipJ_CPIJ003516, anticorps Tsp_03939, anticorps stam-1, anticorps Stam, anticorps stam
- Sujet
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Synonyms: Signal transducing adapter molecule 1, Signal transducing adapter molecule 2, Signal transducing adaptor molecule SH3 domain and ITAM mot 1, Signal transducing adaptor molecule, STAM 1, STAM-2, STAM1, Stam2, STAM2_HUMAN, DKFZp686J2352, Hrs-binding protein, HSE1 homolog, OTTHUMP00000019237.
Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
- ID gène
- 8027
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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