ALOX5 anticorps (pSer271) (Alexa Fluor 488)
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- Antigène Voir toutes ALOX5 Anticorps
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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Épitope
- pSer271
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ALOX5 est conjugé à/à la Alexa Fluor 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from rat 5-Lipoxygenase around the phosphorylation site of Ser271
- Isotype
- IgG
- Top Product
- Discover our top product ALOX5 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
- Autre désignation
- 5-Lipoxygenase (ALOX5 Produits)
- Synonymes
- anticorps 5-LO, anticorps 5-LOX, anticorps 5LPG, anticorps LOG5, anticorps 5LO, anticorps 5LX, anticorps AI850497, anticorps F730011J02, anticorps LOX5A, anticorps si:dkey-194n13.2, anticorps lox5, anticorps arachidonate 5-lipoxygenase, anticorps arachidonate 5-lipoxygenase a, anticorps Arachidonate 5-lipoxygenase, anticorps ALOX5, anticorps Alox5, anticorps alox5a, anticorps AFUA_4G02770, anticorps AOR_1_1362014, anticorps lox5
- Sujet
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Synonyms: 5-lipoxygenase, 5 LO, 5LPG, ALOX 5, ALOX5, Arachidonate 5 lipoxygenase, Arachidonic acid 5 lipoxygenase, Leukotriene A4 synthase, LOG 5, LOG5, MGC163204, LOX5_HUMAN.
Background: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
- ID gène
- 240
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