TCP1 alpha/CCTA anticorps (pSer455) (Alexa Fluor 350)

N° du produit ABIN876245

Détail du produit anti-TCP1 alpha/CCTA anticorps (Alexa Fluor 350)

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Épitope: pSer455

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCP1 alpha/CCTA est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human p63 around the phosphorylation site of Ser455

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TCP1 alpha/CCTA

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Autre désignation: P63 (TCP1 Produits)

Synonymes: anticorps CCT-alpha, anticorps CCT1, anticorps CCTa, anticorps D6S230E, anticorps TCP-1-alpha, anticorps AI528772, anticorps CCT, anticorps Cct1, anticorps Ccta, anticorps TRic, anticorps Tcp-1, anticorps Tp63, anticorps c-cpn, anticorps p63, anticorps TRiC, anticorps CCTalpha, anticorps BEST:GH05123, anticorps CG5374, anticorps Dmel\\CG5374, anticorps T-cpl, anticorps TCP-1alpha, anticorps TCPA_DROME, anticorps Tcp1, anticorps Tcp1-alpha, anticorps gh05123, anticorps cct-alpha, anticorps ccta, anticorps tcp1, anticorps tcp1-a, anticorps tcp1a, anticorps tcp1alpha, anticorps CHUNP6875, anticorps fa13h08, anticorps wu:fa13h08, anticorps wu:fc95g06, anticorps t-complex 1, anticorps T-complex protein 1 subunit alpha, anticorps t-complex protein 1, anticorps Tcp1-like, anticorps t-complex 1 S homeolog, anticorps TCP1, anticorps cct-1, anticorps Tcp1, anticorps T-cp1, anticorps tcp1.S, anticorps tcp1

Sujet:

Synonyms: p63 phospho S455, p63 phospho Ser455, p-p63 Ser455, AIS, Amplied in squamous cell carcinoma, Bp51A, Bp51B, p63 Alpha, Chronic ulcerative stomatitis protein, CUSP, DN p63 alpha 1, DNp63, EEC3, Keratinocyte transcription factor, Keratinocyte transcription factor KET, KET, LMS, NBP, OFC8, p40, p51, P51/P63, p53 like transcription factor, p53 related protein, p53-related protein p63, p53CP, p63, P73, p73H, p73L, RHS, SHFM4, TP53CP, TP53L, TP63, TP73, TP73L, Transformation related protein 63, Trp53rp1, Trp63, Tumor protein 63, tumor protein 63 kDa with strong homology to p53, Tumor protein p53-competing protein, Tumor protein p53-like, tumor protein p63, Tumor protein p73, tumor protein p73-like, P63_HUMAN.

Background: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].

ID gène: 8626