ABL2 anticorps (AA 935-1050) (Alexa Fluor 488)

N° du produit ABIN880973

Détail du produit anti-ABL2 anticorps (Alexa Fluor 488)

Antigène: ABL2

Épitope: AA 935-1050

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABL2 est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ABL2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ABL2

Antigène: ABL2

Autre désignation: ABL2 (ABL2 Produits)

Synonymes: anticorps ABLL, anticorps ARG, anticorps Abll, anticorps Arg, anticorps AA536808, anticorps ABL proto-oncogene 2, non-receptor tyrosine kinase, anticorps v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene), anticorps ABL2, anticorps Abl2

Sujet:

Synonyms: Abelson murine leukemia viral oncogene homolog 2, Abelson related gene protein, Tyrosine kinase ARG, ABLL,ARG,Tyrosine protein kinase ABL2, v abl Abelson murine leukemia viral oncogene homolog 2, ABL2_HUMAN, Abelson tyrosine-protein kinase 2, Tyrosine-protein kinase ARG.

Background: ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. It is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas. Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified. The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments.

ID gène: 27