BTG1, BTG2 (AA 41-140) anticorps (Alexa Fluor 647)

N° du produit ABIN885717

Détail du produit

Antigène: BTG1, BTG2

Épitope: AA 41-140

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BTG1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: BTG1, BTG2

Autre désignation: BTG1 and BTG2

Sujet:

Synonyms: B cell translocation gene 1 protein, B cell translocation gene 1, anti prolerative, BTG1 protein, BTG1_HUMAN, BTG2_HUMAN, Protein BTG2, BTG family member 2, NGF-inducible anti-prolerative protein PC3, pheochromacytoma cell-3, nerve growth factor-inducible anti-prolerative, B-cell translocation gene 2, BTG2, TIS21, PC3, TIS21

Background: BTG1 belongs to the BTG family of proteins.FUNCTION: Anti-proliferative protein. Its expression is associated with the early G1 phase of the cell cycle. A chromosomal aberration involving BTG1 may be a cause of a form of B cell chronic lymphocytic leukemia, translocation t(8,12)(q24,q22) with MYC. BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF), suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398).

ID gène: 694, 7832

UniProt: P62324, P78543